Tetrazoles of manno- and rhamno-pyranoses: inhibition of glycosidases by tetrazoles and other mannose mimics
Brandstetter TW., Davis B., Hyett D., Smith C., Hackett L., Winchester BG., Fleet GWJ.
The synthesis of tetrazoles derived from D-mannopyranose and D-rhamnopyranose from L-gulonolactone is described. These and other materials are assessed as inhibitors of human liver glycosidases and delineate some structural features required for α- and β-mannosidase and α-fucosidase inhibition. © 1995.