Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate gives rapid access to precursors for second messenger analogues
Riley AM., Godage HY., Mahon MF., Potter BVL.
Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate via the formation of diastereoisomeric bis[(1S)-(-)-camphanate] esters provides a convenient and fast route to precursors for biologically important inositol phosphates and lipids, and to synthetic analogues and probes modified at O-1 or O-3 of the inositol ring. © 2005 Elsevier Ltd. All rights reserved.