Opportunities
Fellowship Opportunities
The Department is happy to host prospective and future fellowship grant holders and offers a competitive start-up package for early career researchers seeking to carry out their research in Oxford.
Current vacancies
Postdoctoral Research Assistant in Medicinal Chemistry and Antimicrobial Resistance
Grade 7: £33,309-£40,927 per annum
Applications are invited for a Postdoctoral Research Associate to join a research team developing new approaches to combat antimicrobial resistance, working under the supervision of Dr Thomas Lanyon-Hogg for a period of 12 months. This project is funded by the Medical Research Council and will be carried out in the Department of Pharmacology, University of Oxford, in close collaboration with the Sir William Dunn School of Pathology, University of Oxford.
This is an exciting opportunity to work with world-leading researchers and contribute to the development of innovative new approaches in a significant area of unmet medical need. Find out more about the Lanyon-Hogg group’s research at: https://www.pharm.ox.ac.uk/research/lanyon-hogg-group
This role will involve the design and synthesis of small molecules and peptides and transitioning synthetic strategies to automated platforms.
You must have experience in small molecule and peptide synthesis and in medicinal chemistry. You must also hold (or be close to completion prior to taking up appointment) a relevant PhD/DPhil in medicinal chemistry, organic synthesis, or chemical biology, together with relevant experience. Previous experience of automated synthesis, antibiotic drug discovery and biochemistry and microbiology would be an advantage.
The post is fixed-term for 12 months, funded by the Medical Research Council and is available from mid-January 2024.
The closing date for applications is 12noon on Friday 24 November 2023.
Apply online on the University website
Postdoctoral Research Assistant in Cardiac Signalling
Grade 7: £33,309-£40,927 per annum
We are looking for a well-trained, highly motivated laboratory scientist with extensive experience in cardiac drug discovery to join our research team to develop innovative treatment for Hypertrophic cardiomyopathy (HCM). The successful candidate will be a member of the Cardiac Signalling Group by Ming Lei at Department of Pharmacology and be affiliated with the Inherited Heart Muscle Disease Group led by Professor Hugh Watkins FRS FMedSci. The post holder is also expected to provide guidance to less experienced members of the research group, including postdocs, research assistants, technicians, and PhD and project students.
HCM is the most common inherited cardiac disease with a prevalence of 1:200-1:500 and is a leading cause of sudden death in young adults and athletes particularly. Genetic studies indicated that HCM-causing mutations are commonly found in sarcomere genes (eg MYH7, MYBPC3, and ACTC1). However, despite significant progress in identifying disease-causing gene mutations and clinical interventions for symptoms and risk mitigation of sudden death, there is still a lack of effective and specific treatments for mitigating the disease progression of HCM. The overall aim of the project is to determine the role of P21 activated kinases as a target for the management of disease progression in HCM and clarify the mechanisms of drug action.
You will need to manage your own academic research and administrative activities and co-ordinate multiple aspects of work to meet deadlines. You will be expected to adapt existing and develop new scientific techniques and experimental protocols; test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate; contribute ideas for new research projects; and collaborate in the preparation of scientific reports and journal articles and occasionally present papers and posters. You will also be expected to contribute up to 2 hours of teaching per week at the direction of the Head of Department as a contribution to your career development.
You must hold a relevant PhD/DPhil in Pharmacology, Medicine or a related discipline (or be close to completion); possess sufficient specialist knowledge in the discipline of pharmacology and medicine to work within established research programmes; and must have experience in various cardiac in vivo techniques and electrophysiology.
Fixed-term for 32 months (20 months in Pharmacology and 12 months in the Radcliffe Deparrtment of Medicine), funded by the British Heart Foundation
The closing date for applications is 12noon on Friday 24 November 2023.
Apply online on the University website