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The Department mourns the loss of three greats in neuropharmacology
11 August 2020
This summer three of the world’s most distinguished neurochemists died; each was a member of the Department during their outstanding scientific careers.
Professor Fran Platt secures £1M funding over two years for vital Parkinson's Disease research, in collaboration with Pfizer
4 August 2020
There is an increasing body of genetic and biochemical evidence that points toward lysosomal dysfunction as a risk factor for developing age-related neurodegenerative disorders, including Parkinson’s disease (PD).
New Galione group paper explores the role for early Ca2+ signals in phagocytosis
9 June 2020
The Galione Lab has a paper published in The EMBO Journal showing that local Ca2+‐nanodomains formed by two‐pore channels (TPCs) on endo-lysosomes are shown to drive phagocytosis in macrophages. Moreover, different endo-lysosomal Ca2+ channels do different jobs at phagocytosis (extreme compartmentation).