The feeling of being tired is familiar to everyone. As we know from our own experience, an extended period of wakefulness results in a decline in our performance levels, and the desire to sleep becomes almost irresistible. When you then fall asleep, your sleep is deeper and more consolidated than usual. And yet after just one night of uninterrupted sleep, you can feel refreshed and \u201cback to normal\u201d!
Pathological hyperphosphorylated forms of the microtubule-associated binding protein Tau (pTau) are commonly found in people with neurodegenerative diseases, including Alzheimer\u2019s disease, Corticobasal degeneration, and Progressive supranuclear palsy.
At the start of this year, we have welcomed 23 new MSc in Pharmacology students, 13 new MSc(Res) and DPhil students and around a dozen additional project and visiting students from other Departments and other Universities. Some of these new starters joined existing staff, students and visitors in the Department for the first of a series of group photographs, to be taken every 6 months for our archives.
Congratulations to Yuzhe Weng, a DPhil student in the Platt lab, who is first author on new paper published by the group in Nature Communications. \r\n\r\nMycobacteria tuberculosis (Mtb), the causative agent of tuberculosis (TB), has the ability to invade, persist and replicate within host cells, which is key to its success as a pathogen. However, the mechanisms that underlie this strategy remain poorly defined.
A new paper, published this week in the journal Science, highlights cutting-edge imaging techniques used by the group of Professor Ben Davis to investigate the binding of SARS-CoV-2 to human cells.
Pharmacology Head of Department, Professor Fran Platt, has been announced as the winner of the 2023 Thudichum Medal, presented by the Biochemical Society.
Two year fellowship, offered in association with Linacre College, which offers full salary support, funding for travel and consumables and college accommodation. Join one of the existing groups in Pharmacology and develop your own research programme.
The Department of Pharmacology is delighted to announce the appointment of Sir Jonathan Symonds CBE, Chair of the Board of GlaxoSmithKline, as a Visiting Fellow. Jon has been Chairman of the Board at GSK since September 2019.
The Rosalind Franklin Institute and the University of Oxford\u2019s Department of Pharmacology have entered into a strategic partnership for Next Generation Chemistry.
A new paper, published by the Tammaro lab in the Proceedings of the National Academy of Sciences (PNAS), shines new light on potential sites for pharmacological intervention within TMEM16A channels.
A new study, led by Professor Kim Dora in association with Professor Raimondo Ascione at the University of Bristol, has shown abnormalities in the tiny blood vessels of human hearts which cannot be detected by current heart scans. Poor myogenic (automatic) tone, where blood flow in these vessels is abnormal, is thought to develop independent of disease in the larger arteries, which can be treated using stents or bypass surgeries.
We were delighted to learn from the announcement today, 6 May 2021, that Professor Fran Platt has been elected a Fellow of The Royal Society. She is one of the 52 distinguished scientists whose election was announced, and one of the two biologists out of six Oxford academics so-honoured this year.\r\nhttps://royalsociety.org/news/2021/05/new-fellows-announcement-2021/
![\"Wakefulness](\"https://www.pharm.ox.ac.uk/news/raised-intracellular-chloride-levels-underlie-the-effects-of-tiredness-in-cortex/responsive_image?ratio=r16x9&scale=w760\")
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