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In drug development programmes, multiple assays are needed for the determination of protein-compound interactions and evaluation of potential use in assays with protein-protein interactions. In this protocol we describe the waterLOGSY NMR method for confirming protein-ligand binding events.

Original publication

DOI

10.21769/BioProtoc.3666

Type

Journal article

Journal

Bio Protoc

Publication Date

05/07/2020

Volume

10

Keywords

Drug discovery, Drugs, Ligand binding, NMR, Protein-protein interaction, WaterLOGSY