Oxygen chiral phosphate in ribo- and 2'-deoxyribodinucleoside monophosphates by oxidation of phosphite intermediates
Seela F., Ott J., Potter BVL., Herdering W.
Chromatographic separation of the isomers followed by deprotection yielded oxygen chiral dinucleoside monophosphates. The absolute configuration of [10O]UpA has been established. Oxidation of dinucleoside monoDhosDhi.te triesters of ribo and deoxyribonucleosides with iodine-H2O furnished diastereoisomeric phosphate triesters having the oxygen labels in the P=0 group. © 1985, Taylor & Francis Group, LLC. All rights reserved.