Flow chemistry kinetic studies reveal reaction conditions for ready access to unsymmetrical trehalose analogues.
Patel MK., Davis BG.
Monofunctionalization of trehalose, a widely-found symmetric plant disaccharide, was studied in a microreactor to give valuable kinetic insights that have allowed improvements in desymmetrization yields and the development of a reaction sequence for large scale monofunctionalizations that allow access to probes of trehalose's biological function.