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A broad substrate specificity for adenosine 5′-diphosphate ribosyl cyclase is demonstrated by cyclisation of ribose-and purine-modified nicotinamide adenine dinucleotide analogues to mimics of cyclic adenosine 5′-diphosphate ribose, generating a straightforward route for structural modification of this important Ca2+-mobilising nucleotide.

Original publication

DOI

10.1039/C39950001359

Type

Journal article

Journal

Journal of the Chemical Society, Chemical Communications

Publication Date

01/12/1995

Pages

1359 - 1360