Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The pharmacology of the TMEM16A channel: therapeutic opportunities.

Journal article

Al-Hosni R. et al, (2022), Trends Pharmacol Sci

TMEM16A channel is a key regulator of cerebral blood flow at the capillary level

Conference paper

Ilkan Z. et al, (2022), BIOPHYSICAL JOURNAL, 121, 176A - 176A

Polymodal Control of TMEM16x Channels and Scramblases

Journal article

Agostinelli E. and Tammaro P., (2022), International Journal of Molecular Sciences, 23

An outer-pore gate modulates the pharmacology of the TMEM16A channel.

Journal article

Dinsdale RL. et al, (2021), Proc Natl Acad Sci U S A, 118

Ion channels as convergence points in the pathology of pulmonary arterial hypertension.

Journal article

Jouen-Tachoire TRH. et al, (2021), Biochem Soc Trans

The Molecular Basis of the Regulation of the TMEM16A Ca2+-Activated Cl- Channel by the Lysosomal NPC1 Protein

Conference paper

Scofano LF. et al, (2021), BIOPHYSICAL JOURNAL, 120, 247A - 247A

Lipid-mediated control of the TMEM16A Ca2+- gated Cl- channel by the lysosomal NPC1 protein

Conference paper

Scofano LF. et al, (2021), BRITISH JOURNAL OF PHARMACOLOGY, 178, 414 - 414

Molecular Mechanism of Modulation of the TMEM16A Channel by Anthracene-9-Carboxylic Acid: Implications for Channel Gating

Conference paper

Dinsdale R. et al, (2020), BIOPHYSICAL JOURNAL, 118, 325A - 325A

Control of cerebral blood flow by capillary pericytes in Alzheimer's disease

Conference paper

Korte N. et al, (2019), ACTA PHYSIOLOGICA, 227

Inhibition of TMEM16A by Docosahexaenoic Acid Plays a Crucial Role in Blood Vessel Relaxation

Conference paper

Acheson KE. and Tammaro P., (2019), BIOPHYSICAL JOURNAL, 116, 172A - 172A

Defining the ionic mechanisms of optogenetic control of vascular tone by channelrhodopsin-2.

Journal article

Rorsman NJG. et al, (2018), Br J Pharmacol, 175, 2028 - 2045

Contrasting effects of phosphatidylinositol 4,5-bisphosphate on cloned TMEM16A and TMEM16B channels.

Journal article

Ta CM. et al, (2017), Br J Pharmacol, 174, 2984 - 2999

Mechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blocker.

Journal article

Ta CM. et al, (2016), Br J Pharmacol, 173, 511 - 528

Putative pore-loops of TMEM16/anoctamin channels affect channel density in cell membranes.

Journal article

Adomaviciene A. et al, (2013), J Physiol, 591, 3487 - 3505

Load More