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Optimisation of tetrahydroisoquinoline-based chimeric microtubule disruptors.

Journal article

Dohle W. et al, (2014), ChemMedChem, 9, 1783 - 1793

Synthesis, anti-tubulin and antiproliferative SAR of steroidomimetic dihydroisoquinolinones.

Journal article

Leese MP. et al, (2014), ChemMedChem, 9, 798 - 812

Synthesis, antitubulin, and antiproliferative SAR of C3/C1-substituted tetrahydroisoquinolines.

Journal article

Dohle W. et al, (2014), ChemMedChem, 9, 350 - 370

Tetrahydroisoquinolinone-based steroidomimetic and chimeric microtubule disruptors.

Journal article

Leese MP. et al, (2014), ChemMedChem, 9, 85 - 1

Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors.

Journal article

Leese MP. et al, (2012), ACS Med Chem Lett, 3, 5 - 9

Structure-activity relationships of C-17-substituted estratriene-3-O-sulfamates as anticancer agents.

Journal article

Jourdan F. et al, (2011), J Med Chem, 54, 4863 - 4879

Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate.

Journal article

Jourdan F. et al, (2010), J Med Chem, 53, 2942 - 2951

A protecting group free synthesis of (+/-)-neostenine via the [5 + 2] photocycloaddition of maleimides.

Journal article

Lainchbury MD. et al, (2008), J Org Chem, 73, 6497 - 6505

Copper-catalysed meso-bislactone ring opening using Grignard and mixed triorganozinc reagents

Journal article

Borthwick S. et al, (2006), Tetrahedron Letters, 47, 7205 - 7208

A practical flow reactor for continuous organic photochemistry.

Journal article

Hook BDA. et al, (2005), J Org Chem, 70, 7558 - 7564

Highly functionalized organomagnesium reagents prepared through halogen-metal exchange.

Journal article

Knochel P. et al, (2003), Angew Chem Int Ed Engl, 42, 4302 - 4320

Synthesis of polyfunctional indoles and related heterocycles mediated by cesium and potassium bases

Journal article

Koradin C. et al, (2003), Tetrahedron, 59, 1571 - 1587

Preparation and reactions of functionalized arylmagnesium reagents

Journal article

Jensen AE. et al, (2002), Synthesis, 565 - 569

Functionalized main-group organometallics for organic synthesis

Conference paper

Knochel P. et al, (2002), Pure and Applied Chemistry, 74, 11 - 17

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