Research groups
Colleges
Daniel C Anthony
Professor of Experimental Neuropathology
- Fellow of Somerville College
- Honorary Professor, University of Southern Denmark
- Fellow of the British Pharmacological Society
Daniel Anthony, a specialist in inflammatory disease, leads the Experimental Neuropathology Laboratory at the University of Oxford. As a Fellow of Somerville College and an Honorary Professor at the University of Southern Denmark, he has developed a niche in understanding how systemic inflammation influences the outcomes of both acute and chronic brain injuries and infections. His research interests also focus on the role of circulating extracellular vesicles in the pathogenesis of CNS diseases and the contribution of cytokine production to neuropsychiatric disorders.
Professor Anthony's career began with a Ph.D. from University College London in 1994, after which he joined Professor Hugh Perry in Oxford on a British Biotech Fellowship to explore metalloproteinase expression in the CNS. His work has led to the identification of novel biomarkers for diagnosing disease and predicting progression, leveraging a combination of in vivo biology, molecular biology, immunohistochemistry, MRI and PET imaging, and metabolomics. After a stint at the University of Southampton, where he was a Lecturer in Neurobiology, he returned to Oxford in 2004, where he continues to explore the neurobiology of inflammation with research collaborations throughout the world. In 2015, he was awarded a personal Chair in Experimental Neuropathology, and he was made a Fellow of the British Pharmacological Society in 2020.
Recent publications
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Intriguing astrocyte responses in CA1 to reduced and rehabilitated masticatory function: Dorsal and ventral distinct perspectives in adult mice
Journal article
Castro MML. et al, (2025), Archives of Oral Biology, 169, 106097 - 106097
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Extraction Methods for Brain Biopsy NMR Metabolomics: Balancing Metabolite Stability and Protein Precipitation
Journal article
Xiong W. et al, (2024), Metabolites, 14, 609 - 609
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The Hidden Dangers of Sedentary Living: Insights into Molecular, Cellular, and Systemic Mechanisms
Journal article
Diniz DG. et al, (2024), International Journal of Molecular Sciences, 25, 10757 - 10757
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Metformin reprograms tryptophan metabolism via gut microbiome-derived bile acid metabolites to ameliorate depression-Like behaviors in mice.
Journal article
Xie X. et al, (2024), Brain Behav Immun, 123, 442 - 455
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Sedentary Life Is an Invisible Trap: Molecular, Cellular, and Systemic Reasons to Leave It Behind
Preprint
Diniz DG. et al, (2024)