Xiangdong Su

My research focuses on the design, synthesis and chemical biological study of small molecules that play important roles in regulating cellular function and metabolism. In the past I have worked on small molecule inhibitors of enzymes that regulate corticosteroids metabolism within cells, which may potentially be used to develop new drugs for the treatment of metabolic related disorders. I have also worked in the discovery of new generation of antimicrobial molecules that showed inhibiting activity against drug resistant bacterial.

My current research work focuses on the synthesis of analogues of adenophostin A, which is potent agonist of inositol triphosphate (IP3) receptor. These molecules are crucial in Calcium ion signalling process within cells and play key roles on different cellular functions.