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The first member of a novel class of chemoselective reagents, glycosyl methanedithiosulfonates, has been synthesized, identified and employed in the first examples of chemical, site-selective construction of a trisulfide-modified protein with complete conversion.

Original publication

DOI

10.1039/b706682a

Type

Journal article

Journal

Chem Commun (Camb)

Publication Date

14/08/2007

Pages

3145 - 3147

Keywords

Alkanesulfonates, Crystallography, X-Ray, Glycoproteins, Protein Conformation, Sulfides