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Synthesis of a biologically potent inositol polyphosphate analogue, myo-inositol 1,4,5-triphosphate-3-O-methylene carboxylate incorporating an efficient oxidative cleavage of an O-allyl ether in the presence of protected phosphate triesters is described.

Original publication




Journal article


Journal of the Chemical Society, Chemical Communications

Publication Date



1687 - 1689