Convergent synthesis of adenophostin A analogues via a base replacement strategy
Marwood RD., Shuto S., Jenkins DJ., Potter BVL.
The first totally synthetic base-modified analogues of the natural product and potent D-myo-inositol 1,4,5-trisphosphate receptor agonist adenophostin A were efficiently synthesised from D-xylose and D-glucose using methodology employing base and surrogate base addition to a common disaccharide intermediate.