Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Search results (55)

« Back to Publications

TRPML1 suppresses pulmonary fibrosis by limiting collagen and elastin deposition.

Weiden E-M. et al, (2026), EMBO J

Proton-selective conductance and gating of the lysosomal cation channel TMEM175.

Schulze T. et al, (2026), Proc Natl Acad Sci U S A, 123

Direct measurements of luminal Ca2+ with endo-lysosomal GFP-aequorin reveal functional IP3 receptors.

Calvo B. et al, (2025), J Cell Biol, 224

Physiological functions and pharmacological targeting of transient receptor potential channels.

Chubanov V. et al, (2025), Pharmacol Rev, 77

TRPML2 channel modulation by PI(3,5)P₂ and small-molecule agonists controls endosomal vesicle dynamics.

Gu Z-Q. et al, (2025), Biomed Pharmacother, 189

TPCs: FROM PLANT TO HUMAN.

Klingl YE. et al, (2025), Physiol Rev, 105, 1695 - 1732

TRPML2 in distinct states reveals the activation and modulation principles of the TRPML family.

Schmiege P. et al, (2025), Nat Commun, 16

Lysosomal TMEM165 controls cellular ion homeostasis and survival by mediating lysosomal Ca2+ import and H+ efflux.

Chen R. et al, (2025), Nat Commun, 16

Lysosomal TPC2 channels disrupt Ca2+ entry and dopaminergic function in models of LRRK2-Parkinson's disease.

Gregori M. et al, (2025), J Cell Biol, 224

Unraveling pH Regulation of TMEM175, an Endolysosomal Cation Channel With a Role in Parkinson's Disease.

Schulze T. et al, (2025), J Cell Physiol, 240

TPC2: From Blond Hair to Melanoma?

Abrahamian C. et al, (2024), Cancers (Basel), 16

Rab7a is an enhancer of TPC2 activity regulating melanoma progression through modulation of the GSK3β/β-Catenin/MITF-axis.

Abrahamian C. et al, (2024), Nat Commun, 15

Expression Profiling Identified TRPM7 and HER2 as Potential Targets for the Combined Treatment of Cancer Cells.

Egawa M. et al, (2024), Cells, 13

Endolysosomal TRPML1 channel regulates cancer cell migration by altering intracellular trafficking of E-cadherin and β1-integrin.

Frey N. et al, (2024), J Biol Chem, 300

TRPML3/BK complex promotes autophagy and bacterial clearance by providing a positive feedback regulation of mTOR via PI3P.

Xu M. et al, (2023), Proc Natl Acad Sci U S A, 120

Load More