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Publications

Histamine, Neuroinflammation and Neurodevelopment: A Review

Carthy E. and Ellender T., (2021), Frontiers in Neuroscience, 15

An iPSC model of Hereditary Sensory Neuropathy type-1 reveals Serine responsive deficits in neuronal ganglioside composition and axoglial interactions

CLARK A., (2021), Cell Reports Medicine

Nafamostat reduces systemic inflammation in TLR7-mediated virus-like illness

Yates AG. et al, (2021)

Lipid-mediated impairment of axonal lysosome transport contributing to autophagic stress.

Roney JC. et al, (2021), Autophagy

Choreographing endo-lysosomal Ca2+ throughout the life of a phagosome.

Morgan AJ. et al, (2021), Biochim Biophys Acta Mol Cell Res, 1868

Clinical Validation of Optimised RT-LAMP for the Diagnosis of SARS-CoV2 infection

HUANG WEI., (2021), Scientific Reports

Glucose and NAADP trigger elementary intracellular β-cell Ca2+ signals.

Heister PM. et al, (2021), Sci Rep, 11

Anti-CD20 Disrupts Meningeal B-Cell Aggregates in a Model of Secondary Progressive Multiple Sclerosis.

Roodselaar J. et al, (2021), Neurol Neuroimmunol Neuroinflamm, 8

Non-neuronal cells in amyotrophic lateral sclerosis - from pathogenesis to biomarkers.

Vahsen BF. et al, (2021), Nat Rev Neurol

Diversity in striatal synaptic circuits arises from distinct embryonic progenitor pools in the ventral telencephalon.

van Heusden F. et al, (2021), Cell Rep, 35

MULTIPLE SUBSTRATE RECOGNITION BY YEAST DIADENOSINE AND DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE THROUGH PHOSPHATE CLAMPING

POTTER B. et al, (2021), Science Advances

Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy.

Vuorinen A. et al, (2021), Eur J Med Chem, 220

Cardiac TdP risk stratification modelling of anti-infective compounds including chloroquine and hydroxychloroquine.

Whittaker DG. et al, (2021), R Soc Open Sci, 8

Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C.

Roney JC. et al, (2021), Dev Cell

Adenosine integrates light and sleep signalling for the regulation of circadian timing in mice.

Jagannath A. et al, (2021), Nat Commun, 12

Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni.

Partridge FA. et al, (2021), ACS Infect Dis

A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2.

Bery N. et al, (2021), Sci Adv, 7

COSMAS: A lightweight toolbox for cardiac optical mapping analysis

BURTON R-A. et al, (2021), Scientific Reports

Emerging evidence for cAMP-Ca2+ cross talk in heart atrial nanodomains where IP3-evoked Ca2+ release stimulates adenylyl cyclases

BURTON R-A. and Derek T., (2021), Sage Open

Photochemical probe identification of a small-molecule inhibitor binding site in Hedgehog acyltransferase (HHAT)

Lanyon-Hogg T. et al, (2021), Angewandte Chemie International Edition

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