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Publications

Small Molecule CD38 Inhibitors: Synthesis of 8-Amino-N1-Inosine 5'-Monophosphate, Analogues and Early Structure-Activity Relationship

Potter B. and Watt J., (2021), Molecules

Substituted Aryl Benzylamines as Potent and Selective Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 3

Potter B., (2021), Molecules

VESICLE CHOLESTEROL CONTROLS EXOCYTOTIC FUSION PORE

PLATT F. and Frances P., (2021), Cell Calcium

International consensus on clinical severity scale use in evaluating Niemann-Pick disease Type C in paediatric and adult patients: results from a Delphi Study

PLATT F., (2021), Orphanet Journal of Rare Diseases

Glycosphingolipid metabolism and its role in ageing and Parkinson's disease.

Wallom K-L. et al, (2021), Glycoconj J

Ventricular SK2 upregulation following angiotensin II challenge: Modulation by p21-activated kinase-1.

Yang B. et al, (2021), J Mol Cell Cardiol

The V2475F CPVT1 mutation yields distinct RyR2 channel populations that differ in their responses to cytosolic Ca2+ and Mg2.

Wilson AD. et al, (2021), J Physiol

A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells In Vitro and Shows Antitumor Effects In Vivo

Josa-Culleré L. et al, (2021), Journal of Medicinal Chemistry

Tonic GABAA receptor mediated currents of human cortical GABAergic interneurons vary amongst cell types.

Field M. et al, (2021), J Neurosci

Quantal Ca2+ release mediated by very few IP3 receptors that rapidly inactivate. Allows graded responses to IP3

POTTER B. and RILEY AM., (2021), Cell Reports

Somnotate: A robust automated sleep stage classifier that exceeds human performance and identifies ambiguous states in mice

Brodersen PJN. et al, (2021)

Contributing to Understand the Crosstalk between Brain and Periphery in Methylmercury Intoxication: Neurotoxicity and Extracellular Vesicles.

Arrifano GDP. et al, (2021), Int J Mol Sci, 22

Disrupting epileptiform activity by preventing parvalbumin interneuron depolarization block

AKERMAN C., (2021), The Journal of Neuroscience

A modified density gradient proteomic-based method to analyze endolysosomal proteins in cardiac tissue.

Ayagama T. et al, (2021), iScience, 24

In sickness and in health: the functional role of EVs in physiology and pathology in vivo Part II: Pathology

YATES AG. et al, (2021), Journal of Extracellular Vesicles

In sickness and in health: the functional role of EVs in physiology and pathology in vivo Part I: Health and Normal Physiology

YATES AG. et al, (2021), Journal of Extracellular Vesicles

Postnatal prebiotic supplementation in rats affects adult anxious behaviour, hippocampus electrophysiology, metabolomics and gut microbiota.

BURNET P. et al, (2021), iScience

Long-term depression links amyloid-β to the pathological hyperphosphorylation of tau.

Taylor HBC. et al, (2021), Cell Rep, 36

An outer-pore gate modulates the pharmacology of the TMEM16A channel.

Dinsdale RL. et al, (2021), Proc Natl Acad Sci U S A, 118

SPIKE-1: A Randomised Phase II/III trial in a community setting, assessing use of camostat in reducing the clinical progression of COVID-19 by blocking SARS-CoV-2 Spike protein-initiated membrane fusion.

Halford S. et al, (2021), Trials, 22

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