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Publications

Upregulating β-hexosaminidase activity in rodents prevents α-synuclein lipid associations and protects dopaminergic neurons from α-synuclein-mediated neurotoxicity.

PLATT F. and PRIESTMAN D., (2020), Acta Neuropathologica Communications

A blood-based metabolomics test to distinguish relapsing-remitting and secondary progressive multiple sclerosis: addressing practical considerations for clinical application.

Yeo T. et al, (2020), Sci Rep, 10

Histaminergic control of corticostriatal synaptic plasticity during early postnatal development

Han S. et al, (2020), The Journal of Neuroscience

Acetyl-Leucine slows disease progression in lysosomal storage disorders

PLATT F. et al, (2020), Brain Communications

Effects of the putative lithium mimetic ebselen on pilocarpine-induced neural activity.

Singh N. et al, (2020), Eur J Pharmacol

Deconvolution for multimode fiber imaging: Open-source modeling of spatially variant PSF

Turcotte R. et al, (2020), Biomedical Optics Express

2-Arylbenzo[d]oxazole Phosphinate Esters as Second-Generation Modulators of Utrophin for the Treatment of Duchenne Muscular Dystrophy.

Babbs A. et al, (2020), J Med Chem

An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels

POTTER B. and RILEY AM., (2020), Biochemical Journal

Endothelial NO suppresses action-potential-like transient spikes and vasospasm in small resistance arteries

GARLAND C. et al, (2020), Hypertension

Stress-induced aggression in heterozygous TPH2 mutant mice is associated with alterations in serotonin turnover and expression of 5-HT6 and AMPA subunit 2A receptors

Gorlova A. et al, (2020), Journal of Affective Disorders, 272, 440 - 451

Unbiased yeast screens identify cellular pathways affected in Niemann-Pick disease type C.

Colaco A. et al, (2020), Life Sci Alliance, 3

Optical interrogation of sympathetic neuronal effects on macroscopic cardiomyocyte network dynamics

BURTON R-A., (2020), iScience

Defective Platelet Function in Niemann-Pick disease type C1

PLATT F. and COLACO A., (2020), JIMD Communications

Defective Platelet Function in Niemann-Pick disease type C1

COLACO A. and PLATT F., (2020), JIMD Communications

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes.

Hua P. et al, (2020), Blood

Combining tissue engineering and optical imaging approaches to explore interactions along the neuro-cardiac axis

Sigalas C. et al, (2020), ROYAL SOCIETY OPEN SCIENCE, 7

NAADP-regulated two-pore channels drive phagocytosis through endo-lysosomal Ca2+ nanodomains, calcineurin and dynamin.

Davis LC. et al, (2020), EMBO J

Central 5-HT receptors and their function; present and future.

Sharp T. and Barnes NM., (2020), Neuropharmacology

Distinctive binding properties of human monoclonal LGI1 autoantibodies determine pathogenic mechanisms.

Ramberger M. et al, (2020), Brain, 143, 1731 - 1745

A Neurotrophic Mechanism Directs Sensory Nerve Transit in Cranial Bone.

Meyers CA. et al, (2020), Cell Rep, 31

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