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In the late 1960s Miles Vaughan Williams, a member of the staff in the Oxford Department of Pharmacology and Fellow of Hertford College (1955-85), introduced a novel classification of drugs used to treat cardiac arrhythmias. This scheme has been very widely used around the world and has led to the development of new drugs that have saved countless lives. Our understanding of the control of cardiac rhythm has developed in that time and a group of cardiovascular scientists from Oxford, Cambridge and Beijing led by Associate Professor Ming Lei decided that the time was ripe to modernise the classification and to celebrate the centenary of the birth of Vaughan Williams.
Cardiovascular Pharmacology
Research using advanced imaging and electrophysiological techniques to examine the cellular and intracellular mechanisms of the heart and microcirculation
Medicinal Chemistry
Work in the Medicinal Chemistry Group concerns the design, synthesis and biological evaluation of active organic molecules at the interfaces of chemistry and biology
Neuropharmacology
Neuropharmacology is the study of the effects of drugs on the nervous system, aiming to develop compounds to benefit humans with psychiatric and neurological disease
Signalling
Work in the Department includes state of the art subcellular imaging, ion channel electrophysiology (including single channel studies), and the generation of novel molecular and chemical probes to dissect signaling pathways