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New high-resolution imaging provides clue to SARS-CoV-2 leap to humans

Department

A new paper, published this week in the journal Science, highlights cutting-edge imaging techniques used by the group of Professor Ben Davis to investigate the binding of SARS-CoV-2 to human cells.

Dr Mehmood Khan joins Pharmacology as a Visiting Fellow

Department

We are delighted to announce the appointment of Dr Mehmood Khan as a Visiting Fellow in the Department

Fran Platt awarded 2023 Thudichum Medal

Department

Pharmacology Head of Department, Professor Fran Platt, has been announced as the winner of the 2023 Thudichum Medal, presented by the Biochemical Society.

Join Pharmacology as the next Blaschko Fellow

Department

Two year fellowship, offered in association with Linacre College, which offers full salary support, funding for travel and consumables and college accommodation. Join one of the existing groups in Pharmacology and develop your own research programme.

Enhancing the maternal microbiota provides long-term protection against inherited emotional dysfunction

Probiotic supplements administered during pregnancy and nursing improved resilience to mood disorders in the offspring

Sir Jon Symonds joins Pharmacology as a Visiting Fellow

Department

The Department of Pharmacology is delighted to announce the appointment of Sir Jonathan Symonds CBE, Chair of the Board of GlaxoSmithKline, as a Visiting Fellow. Jon has been Chairman of the Board at GSK since September 2019.

Heart neurons use clock genes to control myocyte proliferation

A recent study involving the Minichiello group and international collaborators, principally at the Johns Hopkins University, Baltimore, USA, and the National Institutes of Health, Bethesda, USA, has uncovered an unknown link between cardiac neurons and clock genes in the regulation of heart size and cardiomyocyte proliferation. The lack of appropriate animal models has impaired addressing the precise effect of sympathetic neurons on heart development. The authors have used a novel mouse model based on the deletion of nerve growth factor (NGF) in smooth muscle cells disrupting cardiac sympathetic innervation to demonstrate that sympathetic innervation decreases cardiomyocyte proliferation through clock genes. These novel findings suggest neuronal modulation as a therapeutic strategy for cardiac regeneration.

Rosalind Franklin Institute and Pharmacology announce strategic partnership in Next Generation Chemistry

Department

The Rosalind Franklin Institute and the University of Oxford’s Department of Pharmacology have entered into a strategic partnership for Next Generation Chemistry.

New insight into the pharmacology of a therapeutic ion channel target

Department

A new paper, published by the Tammaro lab in the Proceedings of the National Academy of Sciences (PNAS), shines new light on potential sites for pharmacological intervention within TMEM16A channels.

J Harold Burn (1892-1981)

Department

A world-leading pharmacologist who built up the Department

New BHF study offers potential of new clinical options for cardiac treatment

Department

A new study, led by Professor Kim Dora in association with Professor Raimondo Ascione at the University of Bristol, has shown abnormalities in the tiny blood vessels of human hearts which cannot be detected by current heart scans. Poor myogenic (automatic) tone, where blood flow in these vessels is abnormal, is thought to develop independent of disease in the larger arteries, which can be treated using stents or bypass surgeries.

Professor Fran Platt elected to The Royal Society

Department

We were delighted to learn from the announcement today, 6 May 2021, that Professor Fran Platt has been elected a Fellow of The Royal Society. She is one of the 52 distinguished scientists whose election was announced, and one of the two biologists out of six Oxford academics so-honoured this year. https://royalsociety.org/news/2021/05/new-fellows-announcement-2021/

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