Fay Probert
BSc, MSc, PhD
Dorothy Hodgkin Career Development Fellow
Combining Analytical Chemistry with Multivariate Statistical methods at the interface of Medicine and Biology
Biography
Fay graduated from Warwick University with a BSc in Mathematics before moving to the Department of Chemistry where she completed an MSc in Mathematical Biology and Biophysical Chemistry. Since completing her PhD in Analytical Chemical Biology, Fay has worked at Bruker (UK) and the Medical Research Council (Harwell) applying analytical chemistry techniques, with a focus on NMR spectroscopy, to a range of biological and medical research questions. Throughout her postdoctoral career, Fay’s research has focused on using a multidisciplinary combination of analytical chemistry, mathematics, and biology techniques to understand the chemistry of small molecule pathways associated with disease. In particular, Fay is interested in better understanding the chemical processes associated with inflammation in the brain with the aim of improving the diagnosis and treatment of these diseases.
Fay joined the Department of Pharmacology at Oxford in October 2015 as a senior postdoctoral researcher in the Anthony lab managing a small team of metabolomics researchers and leading several projects which aim to develop NMR metabolomics and multivariate statistical methods to better diagnose, monitor, and predict treatment response in inflammatory diseases of the central nervous system. In 2018, Fay was awarded a Junior Research Fellowship at Somerville College, Oxford.
In 2021 Fay was a awarded a Dorothy Hodgkin Career Development Fellowship in the Chemistry Department.
Fay has received research funding from the MS Society, MRC, EPSRC, BSRC, Merck, and Numares AG.
Recent publications
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Extraction Methods for Brain Biopsy NMR Metabolomics: Balancing Metabolite Stability and Protein Precipitation
Journal article
Xiong W. et al, (2024), Metabolites, 14, 609 - 609
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Using matrix assisted laser desorption ionisation mass spectrometry combined with machine learning for vaccine authenticity screening.
Journal article
Clarke R. et al, (2024), NPJ Vaccines, 9
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Ex-Vivo 13C NMR Spectroscopy of Rodent Brain: TNF Restricts Neuronal Utilization of Astrocyte-Derived Metabolites.
Journal article
Radford-Smith D. et al, (2024), J Proteome Res, 23, 3383 - 3392
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Impact of Serotonin Transporter Absence on Brain Insulin Receptor Expression, Plasma Metabolome Changes, and ADHD-like Behavior in Mice fed a Western Diet.
Journal article
Anthony DC. et al, (2024), Biomolecules, 14
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Plasma H3Cit-DNA Discriminates Between Cancer and Inflammation in a Cohort of Patients with Unspecific Cancer Symptoms.
Journal article
Wannberg F. et al, (2024), Inflammation
