Jacek Szymanski

I have completed my MSc degree at the University of Warsaw, having studied the role of interleukin 6 in the regulation of mouse behaviour at the Nencki Institute of Experimental Biology.

Next, I was awarded a PhD by the University of Valencia, where I researched the genetic and molecular mechanisms underlying neurological disorders with a particular focus on neurodegenerative diseases. As a predoctoral investigator at Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), I was part of a team awarded a grant to study a mutation related to the familial form of Alzheimer’s disease.

I joined the Liliana Minichiello group in February of 2022.

My main interest is understanding the molecular, cellular, and genetic mechanisms governing neurological disorders.

Currently, I study the impact of neurotrophin signalling on the development of neural circuits to comprehend its contribution to cognitive disorders. With the recent establishment of cutting-edge sequencing techniques in the lab, such as RNAseq analysis of single-cell, I wish to identify the sequence of transcriptional and epigenetic changes regulating time-sensitive periods during specific brain circuit development and establish how these are perturbed by the absence of neurotrophin signalling.

I also enjoy supervising students at the laboratory and assisting in general lab management.