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Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase.

Journal article

Ritzefeld M. et al, (2024), J Med Chem, 67, 1061 - 1078

Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.

Journal article

Jamshidiha M. et al, (2022), RSC medicinal chemistry, 13, 150 - 155

Structure, mechanism, and inhibition of Hedgehog acyltransferase.

Journal article

Coupland CE. et al, (2021), Mol Cell, 81, 5025 - 5038.e10

Photochemical Probe Identification of a Small‐Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)**

Journal article

Lanyon‐Hogg T. et al, (2021), Angewandte Chemie, 133, 13654 - 13659

Photochemical probe identification of a small-molecule inhibitor binding site in Hedgehog acyltransferase (HHAT)

Journal article

Lanyon-Hogg T. et al, (2021), Angewandte Chemie International Edition

Direct Targeting of the Ras GTPase Superfamily Through Structure- Based Design

Journal article

Zhao W. et al, (2017), Curr Top Med Chem, 17, 16 - 29

Dynamic Protein Acylation: New Substrates, Mechanisms, and Drug Targets

Journal article

Lanyon-Hogg T. et al, (2017), Trends Biochem Sci, 42, 566 - 581

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