Erdinc Sezgin

I lead the Cell Signalling, Immunity and Nanoimaging (CSI:Nano) Lab at Karolinska Institutet and SciLifeLab, Stockholm, Sweden. My lab works on biophysical principles underlying cellular processes in health and disease. We develop advanced imaging, chemical biology and synthetic biology tools to reveal the molecular mechanisms governing the cellular physiology and disease processes.

We do not yet know what makes some cells fitter than others in the body. Our hypothesis is “the collective physical properties of cells”: physical properties of cells such as stiffness, fluidity, viscosity and charge make some cells more fit (we will call them “physically fit”) that is correlated with their activity. In the lab, we test this by applying novel methodologies designed for the high throughput and single-cell measurement of cellular biophysical properties in combination with machine learning. Moreover, we study nanoscale bioparticles in the body as novel biomarkers of health and disease.

Google Scholar: https://scholar.google.co.uk/citations?user=1JgfAw8AAAAJ&hl=en

Brief CV:

2025-current: EMBO Young Investigator

2024-now  Associate Professor, SciLifeLab, Karolinska Institutet, Stockholm, Sweden

2020-2023  Assistant Professor, SciLifeLab, Karolinska Institutet, Stockholm, Sweden

2018-2019  Newton Fellow, University of Oxford, Oxford, UK.

2015-2017  Marie Skłodowska-Curie Postdoctoral Fellow,University of Oxford, Oxford, UK.

2014-2015  EMBO Postdoctoral Fellow, University of Oxford, Oxford, UK.

2013-2014  Postdoc, Kai Simons Lab, Max Planck Institute of Cell Biology & Genetics, Dresden, Germany

2010-2012  PhD, Petra Schwille Lab, International Max Planck Research School, Dresden, Germany