Professor of Neuropharmacology
- Radcliffe Medical Fellow in Neuroscience, University College Oxford
- Lecturer in Pharmacology, Corpus Christi College Oxford
I graduated in Biochemistry at the University of Birmingham in 1979, and established my interest in neuropharmacology of CNS transmitters in the Department of Physiology and Pharmacology at the University of Nottingham where I obtained my PhD in 1983. I spent the next three years in the Department of Pharmacology at the Karolinska Institute, Stockholm with Urban Ungerstedt as a SERC and Karolinska Institute Overseas Fellow.
In 1986 I joined the MRC Unit of Clinical Pharmacology in Oxford, and was appointed to the MRC External Scientific Staff in 1993. I then joined the Department of Pharmacology in Oxford at the start of the new millennium. Throughout my time in Oxford, my research has focused on the pharmacology and physiology of monoamine transmitters, particularly in relation to the treatment and cause of psychiatric disorder. I hold visiting Professorships with the Universities of Maastricht and Hokkaido. I am currently the Vice-President (Europe) of the International Society for Serotonin Research (ISSR). I was awarded the Irvine Page Lectureship by the ISSR in 2016.
High-frequency stimulation of the subthalamic nucleus modulates neuronal activity in the lateral habenula nucleus.
Hartung H. et al, (2016), Eur J Neurosci, 44, 2698 - 2707
Serotonin, Amygdala and Fear: Assembling the Puzzle.
Bocchio M. et al, (2016), Front Neural Circuits, 10
Effects of the potential lithium-mimetic, ebselen, on impulsivity and emotional processing.
Masaki C. et al, (2016), Psychopharmacology (Berl), 233, 2655 - 2661
Increased Serotonin Transporter Expression Reduces Fear and Recruitment of Parvalbumin Interneurons of the Amygdala.
Bocchio M. et al, (2015), Neuropsychopharmacology, 40, 3015 - 3026
Pharmacological Evidence for 5-HT6 Receptor Modulation of 5-HT Neuron Firing in Vivo.
Brouard JT. et al, (2015), ACS Chem Neurosci, 6, 1241 - 1247
In vivo electrophysiological study of the targeting of 5-HT3 receptor-expressing cortical interneurons by the multimodal antidepressant, vortioxetine.
Schweimer JV. et al, (2022), Eur J Neurosci
Effect of SSRI discontinuation on anxiety-like behaviours in mice
Collins H. et al, (2021)
Psilocin acutely disrupts sleep and affects local but not global sleep homeostasis in laboratory mice
Thomas CW. et al, (2021)