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Site-specific genetic incorporation of unnatural p-halophenylalanine amino acid residues as 'tags' coupled with Pd(0)-mediated Suzuki-Miyuara 'modification' has been enabled by discovery of an effective small molecule palladium scavenger.

Original publication

DOI

10.1039/c0cc04970k

Type

Journal article

Journal

Chem Commun (Camb)

Publication Date

14/02/2011

Volume

47

Pages

1698 - 1700

Keywords

3-Mercaptopropionic Acid, Biocatalysis, Boronic Acids, Chelating Agents, Chromatography, Liquid, Edetic Acid, Furans, Hydrocarbons, Aromatic, Hydrocarbons, Halogenated, Ligands, Maltose-Binding Proteins, Mass Spectrometry, Models, Chemical, Palladium, Phenylalanine