Bacteriostatic activity of fluoro-analogues of 5-(2-hydroxyethyl)-4- methylthiazole, a metabolic intermediate in the biosynthesis of thiamine
Lowe G., Potter BVL.
2-Fluoro-5-(2-hydroxyethyl)-4-methylthiazole and 5-(2-fluoroethyl)-4- methylthiazole have been prepared and the latter converted into a fluoro-analogue of thiamine. All three compounds show bacteriostatic activity against E. coli.