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2-Fluoro-5-(2-hydroxyethyl)-4-methylthiazole and 5-(2-fluoroethyl)-4- methylthiazole have been prepared and the latter converted into a fluoro-analogue of thiamine. All three compounds show bacteriostatic activity against E. coli.

Original publication




Journal article


Journal of the Chemical Society, Perkin Transactions 1

Publication Date



2026 - 2028