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Double agents: dual-action polymers are able to sequester rapidly the marine organism Vibrio harveyi from suspension, while at the same time quenching bacterial quorum sense (QS) signals. The potency of the polymers is assessed by cell aggregation experiments and competitive binding assays against a QS signal precursor, and their effect on bacterial behavior is shown by means of bioluminescence.

Original publication

DOI

10.1002/anie.201103130

Type

Journal article

Journal

Angew Chem Int Ed Engl

Publication Date

10/10/2011

Volume

50

Pages

9852 - 9856

Keywords

Cell Adhesion, Molecular Structure, Polymers, Quorum Sensing, Species Specificity, Structure-Activity Relationship, Surface Properties, Vibrio