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© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Chemical synthesis of glycoproteins through three different strategies, from the same reagent, is herein described. The flexibility of this system, which allows the comparison of different linkage motifs between the same glycan and protein, is shown by one-step diversification of a GlcNAc-ylating reagent and its application in both site-specific and non-site-specific glycoprotein synthesis to create different conjugates from common representative protein scaffolds.

Original publication

DOI

10.1002/ijch.201400182

Type

Journal article

Journal

Israel Journal of Chemistry

Publication Date

01/04/2015

Volume

55

Pages

387 - 391