Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity
Journal article
Márquez-Moñino MÁ. et al, (2024), Nature Communications, 15
Synthesis, biological evaluation, and stability studies of raloxifene mono- and bis-sulfamates as dual-targeting agents
Journal article
Zaraei S-O. et al, (2024), Bioorganic & Medicinal Chemistry, 117645 - 117645
Depleting inositol pyrophosphate 5-InsP7 protected the heart against ischemia-reperfusion injury by elevating plasma adiponectin.
Journal article
Fu L. et al, (2024), Cardiovasc Res
Crystal structure and enzymology of Solanum tuberosum inositol tris/tetrakisphosphate kinase 1 (StITPK1)
Journal article
Potter B. and Shipton M., (2023), Biochemistry
Promising Drug Candidates for the Treatment of Polycystic Ovary Syndrome (PCOS) as Alternatives to the Classical Medication Metformin
Journal article
Potter B. and Dohle W., (2023), European Journal of Pharmacology
Fluorination Influences the Bioisostery of Myo-Inositol Pyrophosphate Analogs
Journal article
Potter B. and RILEY A., (2023), Chemistry a european journal
2-Methoxyestradiol-3,17-O,O-bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells
Journal article
Potter B. and Dohle W., (2023), International Journal of Molecular Sciences
Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein
Journal article
Potter B. and RILEY A., (2023), Science Signaling
2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca2+ entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis
Journal article
Potter B. and Dohle W., (2023), BBA: Molecular Cell Research
Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4
Journal article
Potter B. and RILEY A., (2023), Biochemical Journal
Novel Anti-Acanthamoebic Activities of Irosustat and STX140 and Their Nanoformulations
Journal article
Siddiqui R. et al, (2023), Antibiotics, 12, 561 - 561
Itraconazole inhibits endothelial cell migration by disrupting inositol 2 pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodeling
Journal article
Potter B. et al, (2023), Biomedicine and Pharmacotherapy
Expedient Synthesis and Luminescence Sensing of the Inositol Pyrophosphate Cellular Messenger 5-PP-InsP5
Journal article
Shipton ML. et al, (2023), Chemical Science
Synthesis and in vitro antimicrobial SAR of benzyl and phenyl guanidine and aminoguanidine hydrazone derivatives
Journal article
Potter B. et al, (2022), Molecules
2-Difluoromethoxy-substituted Estratriene Sulfamates: Synthesis, Anti-proliferative SAR, Anti-tubulin Activity and Steroid Sulfatase Inhibition
Journal article
Potter B. et al, (2022), CheMedChem
Lysosomal calcium signalling contributes to acute physiological control of heart rate at the sino-atrial node pacemaker
Conference paper
Capel RA. et al, (2022), ACTA PHYSIOLOGICA, 236, 575 - 577
Cell fate following irradiation of MDA-MB-231- and MCF-7 breast cancer cells pre-exposed to a tetrahydroisoquinoline sulfamate microtubule disruptor
Journal article
Potter B. and Dohle W., (2022), Molecules
A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop
Journal article
Potter BVL. and RILEY AM., (2022), Nature Communications
Small Molecule CD38 Inhibitors: Synthesis of 8-Amino-N1-Inosine 5'-Monophosphate, Analogues and Early Structure-Activity Relationship
Journal article
Potter B. and Watt J., (2021), Molecules
Substituted Aryl Benzylamines as Potent and Selective Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 3
Journal article
Potter B., (2021), Molecules