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Publications

Promising Drug Candidates for the Treatment of Polycystic Ovary Syndrome (PCOS) as Alternatives to the Classical Medication Metformin

Potter B. and Dohle W., (2023), European Journal of Pharmacology

Fluorination Influences the Bioisostery of Myo-Inositol Pyrophosphate Analogs

Potter B. and RILEY A., (2023), Chemistry a european journal

Synthesis and biological activities of flavonoid sulfamates as steroid sulfatase inhibitors

Hejaz HA. et al, (2023), Journal of Medical Pharmaceutical and Allied Sciences, 12, 6025 - 6037

2-Methoxyestradiol-3,17-O,O-bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells

Potter B. and Dohle W., (2023), International Journal of Molecular Sciences

Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein

Potter B. and RILEY A., (2023), Science Signaling

2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca2+ entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis

Potter B. and Dohle W., (2023), BBA: Molecular Cell Research

Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4

Potter B. and RILEY A., (2023), Biochemical Journal

Novel Anti-Acanthamoebic Activities of Irosustat and STX140 and Their Nanoformulations

Siddiqui R. et al, (2023), Antibiotics, 12, 561 - 561

Itraconazole inhibits endothelial cell migration by disrupting inositol 2 pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodeling

Potter B. et al, (2023), Biomedicine and Pharmacotherapy

Expedient Synthesis and Luminescence Sensing of the Inositol Pyrophosphate Cellular Messenger 5-PP-InsP5

Shipton ML. et al, (2023), Chemical Science

Synthesis and in vitro antimicrobial SAR of benzyl and phenyl guanidine and aminoguanidine hydrazone derivatives

Potter B. et al, (2022), Molecules

2-Difluoromethoxy-substituted Estratriene Sulfamates: Synthesis, Anti-proliferative SAR, Anti-tubulin Activity and Steroid Sulfatase Inhibition

Potter B. et al, (2022), CheMedChem

Lysosomal calcium signalling contributes to acute physiological control of heart rate at the sino-atrial node pacemaker

Capel RA. et al, (2022), ACTA PHYSIOLOGICA, 236, 575 - 577

Cell fate following irradiation of MDA-MB-231- and MCF-7 breast cancer cells pre-exposed to a tetrahydroisoquinoline sulfamate microtubule disruptor

Potter B. and Dohle W., (2022), Molecules

A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop

Potter BVL. and RILEY AM., (2022), Nature Communications

Small Molecule CD38 Inhibitors: Synthesis of 8-Amino-N1-Inosine 5'-Monophosphate, Analogues and Early Structure-Activity Relationship

Potter B. and Watt J., (2021), Molecules

Substituted Aryl Benzylamines as Potent and Selective Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 3

Potter B., (2021), Molecules

Quantal Ca2+ release mediated by very few IP3 receptors that rapidly inactivate. Allows graded responses to IP3

POTTER B. and RILEY AM., (2021), Cell Reports

MULTIPLE SUBSTRATE RECOGNITION BY YEAST DIADENOSINE AND DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE THROUGH PHOSPHATE CLAMPING

POTTER B. et al, (2021), Science Advances

Allosteric site on SHIP2 identified through fluorescent ligand screening and crystallography: a potential new target for intervention

POTTER B. et al, (2021), Journal of Medicinal Chemistry

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