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Publications

HDAC inhibitor derivatives induce differentiation of leukemic cells through two distinct and separable mechanisms

Kumar P. et al, (2024)

Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's.

Brimblecombe KR. et al, (2023), Eur J Neurosci

Kinetic insights into agonist-dependent signalling bias at the pro-inflammatory G-protein coupled receptor GPR84.

Luscombe VB. et al, (2023), Eur J Pharmacol, 956

Screening the Medicines for Malaria Pandemic Response Box chemical library onCaenorhabditis elegansidentifies re-profiled candidate anthelmintic drug leads

Nick M. et al, (2022)

A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2.

Bery N. et al, (2021), Sci Adv, 7

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes.

Hua P. et al, (2020), Blood, 136, 2410 - 2415

Aminothiazolones as potent, selective and cell active inhibitors of the PIM kinase family.

Quevedo CE. et al, (2020), Bioorg Med Chem, 28

20 Years an Orphan: Is GPR84 a Plausible Medium-Chain Fatty Acid-Sensing Receptor?

Luscombe VB. et al, (2020), DNA Cell Biol, 39, 1926 - 1937

NMR waterLOGSY as An Assay in Drug Development Programmes for Detecting Protein-Ligand Interactions-NMR waterLOGSY.

Bataille CJR. et al, (2020), Bio Protoc, 10

Anthelmintic drug discovery: target identification, screening methods and the role of open science.

Partridge FA. et al, (2020), Beilstein J Org Chem, 16, 1203 - 1224

Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells

Jain AK. et al, (2020), ACS Applied Bio Materials

Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson’s

Brimblecombe K. et al, (2020)

Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites - Trichuris muris, Brugia malayi, Heligmosomoides polygyrus and Schistosoma mansoni

Partridge F. et al, (2020)

A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages.

Lucy D. et al, (2019), ACS Chem Biol, 14, 2055 - 2064

Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.

Cruz-Migoni A. et al, (2019), Proc Natl Acad Sci U S A, 116, 2545 - 2550

Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors.

Stefaniak J. et al, (2018), ACS Chem Biol, 13, 2849 - 2854

Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment.

Quevedo CE. et al, (2018), Nat Commun, 9

Correction: BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions.

Bery N. et al, (2018), Elife, 7

BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions.

Bery N. et al, (2018), Elife, 7

BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-Effector protein-protein interactions

Bery N. et al, (2018), eLife, 7

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