MA PhD FRS FMedSci
Statutory Professor of Pharmacology
- Wellcome Trust Senior Investigator
- Professorial Fellow of Lady Margaret Hall
- Extraordinary Lecturer in Biochemical Pharmacology, New College
I was educated at Trinity College, Cambridge, and received a BA in Natural Sciences (pharmacology part 2) in 1985 and my PhD (zoology) in 1989, having worked on the role of calcium oscillations in cell activation in Sir Michael Berridge's laboratory.
After a short spell at UCL working on mammalian fertilisation with Michael Whitaker, I went to Johns Hopkins University as a Harkness Fellow studying the role of calcium signals in early development. Returning to the UK in 1991, I joined the Department of Pharmacology. I have been successively a Beit Memorial Fellow, Wellcome Trust Career Development Fellow and Wellcome Trust Senior Fellow in Basic Biomedical Research.
I was elected to a Tutorial Fellowship at New College in 1998 in conjunction with a proleptic University appointment, appointed to a titular Professor of Pharmacology in 2002, and elected to the Professorship of Pharmacology and a Professorial Fellowship at LMH in 2006. I was Head of the Department of Pharmacology from 2006-2015.
I received the 2001 Novartis Prize of the British Pharmacological Society for my scientific contributions to pharmacology. I became a Fellow of the Academy of Medical Sciences in 2010 for my contributions to the advancement of medical science, and in 2016 I was elected a Fellow of The Royal Society for my work on calcium signalling.
Optical profiling of autonomous Ca2+ nanodomains generated by lysosomal TPC2 and TRPML1.
Davis LC. et al, (2023), Cell Calcium, 116
Endolysosomal TPCs regulate social behavior by controlling oxytocin secretion.
Martucci LL. et al, (2023), Proc Natl Acad Sci U S A, 120
Preface. Endolysosomal calcium signalling.
Galione A. and Muallem S., (2023), Cell Calcium, 110
NAADP-Mediated Ca2+ Signalling.
Galione A. et al, (2022), Handb Exp Pharmacol
Acidic Ca2+ stores and immune-cell function.
Davis LC. et al, (2022), Cell Calcium, 101