Carole Bataille
Postdoctoral Research Assistant in Medicinal Chemistry
Key publications
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Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Journal article
Cruz-Migoni A. et al, (2019), Proc Natl Acad Sci U S A, 116, 2545 - 2550
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BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions.
Journal article
Bery N. et al, (2018), Elife, 7
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A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages.
Journal article
Lucy D. et al, (2019), ACS Chem Biol, 14, 2055 - 2064
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Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo.
Journal article
Partridge FA. et al, (2017), PLoS Negl Trop Dis, 11
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Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
Journal article
Bataille CJR. et al, (2017), Bioorg Med Chem, 25, 2657 - 2665
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Hydrogen-bonding-mediated directed osmium dihydroxylation
Journal article
Donohoe TJ. et al, (2011), Organic Reactions, 76, 1 - 48
Recent publications
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Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's.
Journal article
Brimblecombe KR. et al, (2023), Eur J Neurosci
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Screening the Medicines for Malaria Pandemic Response Box chemical library onCaenorhabditis elegansidentifies re-profiled candidate anthelmintic drug leads
Preprint
Nick M. et al, (2022)
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A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2.
Journal article
Bery N. et al, (2021), Sci Adv, 7
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The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes.
Journal article
Hua P. et al, (2020), Blood, 136, 2410 - 2415
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Aminothiazolones as potent, selective and cell active inhibitors of the PIM kinase family.
Journal article
Quevedo CE. et al, (2020), Bioorg Med Chem, 28
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20 Years an Orphan: Is GPR84 a Plausible Medium-Chain Fatty Acid-Sensing Receptor?
Journal article
Luscombe VB. et al, (2020), DNA Cell Biol, 39, 1926 - 1937
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NMR waterLOGSY as An Assay in Drug Development Programmes for Detecting Protein-Ligand Interactions-NMR waterLOGSY.
Journal article
Bataille CJR. et al, (2020), Bio Protoc, 10
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Anthelmintic drug discovery: target identification, screening methods and the role of open science.
Journal article
Partridge FA. et al, (2020), Beilstein J Org Chem, 16, 1203 - 1224