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Edith Sim

Emeritus Professor of Pharmacology

Professor Sim’s current research has arisen from investigation of the molecular basis of different individuals’ responses to environmental chemicals using druginduced immunotoxicity and industrial bladder cancer as model systems. In both of these multi-factorial disorders, polymorphism in metabolism of an environmental chemical by arylamine N-acetyltransferases (NAT) is a key factor. NATs are a unique family of enzymes found in many organisms and form the central theme of her research.