- BBSRC DTP in Interdisciplinary Bioscience
I completed my undergraduate degree in Biomedical Science (BSc Hons) at the University of Sheffield, graduating in 2019. During my time at Sheffield, I was awarded a Wellcome Trust scholarship to investigate disrupted signalling pathways in motor neuron disease. I was also involved in a project generating nociceptive neurons from stem cells and studied the molecular mechanisms of epithelial to mesenchymal cellular transitions in fruit fly development.
I joined the BBSRC Interdisciplinary Bioscience Doctoral Training Programme at the University of Oxford in September 2019. In my first rotation project in the Szele Group (Department of Physiology, Anatomy and Genetics) I worked on the regulation of neurogenesis in the adult hippocampus.
My research aims to determine how different pools of embryonic neural progenitors contribute to the formation and function of neural circuits in the striatum. To do this, I use a range of methodologies including in utero electroporation, single-cell RNA-sequencing, ex vivo electrophysiology and viral synaptic tracing.
Diversity in striatal synaptic circuits arises from distinct embryonic progenitor pools in the ventral telencephalon.
van Heusden F. et al, (2021), Cell Rep, 35