Glycosyl phenylthiosulfonates (glyco-PTS): novel reagents for glycoprotein synthesis.
Gamblin DP., Garnier P., Ward SJ., Oldham NJ., Fairbanks AJ., Davis BG.
Controlled site-selective glycosylation can be achieved by combining site-directed cysteine mutagenesis with chemical modification of the introduced thiol; a new class of more efficient chemoselective reagents, glycosyl phenylthiosulfonates, allow rapid glycosylations of representative simple thiols, peptides and proteins.