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The discovery of novel conditions for highly beta-stereoselective (>9 : 1) mannosylation of OH-2 of mannosides using a straightforward perbenzylthioglycoside donor has allowed ready assembly of beta-mannosyl oligosaccharides including the repeating trisaccharide motif of the O5 antigen of pathogen Klebsiella pneumoniae.

Original publication

DOI

10.1039/b803999m

Type

Journal article

Journal

Org Biomol Chem

Publication Date

07/08/2008

Volume

6

Pages

2692 - 2696

Keywords

Carbohydrate Conformation, Hydroxides, Mannosides, Molecular Structure, Oligosaccharides, Stereoisomerism, Thioglycosides