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The use of a novel bivalent carbohydrate modification reagent, based on a flexible, branched divalent core in a combined site-directed mutagenesis and chemical modification strategy has allowed the first controlled synthesis of a pure protein bearing a branched glycan or a first generation glycodendriprotein.

Original publication

DOI

10.1039/b009184g

Type

Journal article

Journal

Chemical Communications

Publication Date

21/02/2001

Pages

351 - 352