Fe(III)-catalyzed cross-coupling between functionalized arylmagnesium compounds and alkenyl halides
Dohle W., Kopp F., Cahiez G., Knochel P.
Functionalized arylmagnesium reagents bearing an ester, cyano, nonaflate or trialkylsilyloxy group undergo fast cross-coupling reactions with alkenyl iodides or bromides in the presence of catalytic amounts of Fe(acac)3(5 mol%) at-20 °C within 1 hour resulting in the formation of the desired cross-coupling products in satisfactory yields. Excellent yields can be achieved by performing the cross-coupling reaction on solid phase by generating the Grignard reagent on the resin.