Contact information
+44 (0)1865 281129
Research groups
Colleges
Collaborators
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Colin J Akerman
Professor of Neuroscience
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Gemma Gothard
DPhil Student
Matthew Buchan
BSc MSc
DPhil Student
Clarendon Scholar
Biography
I completed a BSc in Neuroscience at the University of St Andrews. Whilst there I worked on a number of projects spanning molecular neuroscience, behaviour and motor control with Dr Gayle Doherty, Dr James Ainge and Professor Gareth Miles before moving to Oxford in 2016.
Research Focus
The mammalian cortex is characterised by specific patterns of synaptic connectivity which are thought to have enabled the development of complex brain processes. A fundamental question in neuroscience is how neurons establish such connections during brain development, thereby adopting unique functional identities within cortical networks.
A number of recent technical advances now make it possible to label specific populations of neurons in the brain, yielding exciting opportunities for the study of cortical development.
Following from the observation that excitatory cortical neurons are generated from a heterogeneous pool of progenitor cells, I am using a combination of in vivo and in vitro electrophysiology, alongside a number of lineage labelling techniques to investigate the extent to which the functional identity of neurons in adult cortical networks is constrained as a function of the progenitor population from which they derive.
Key publications
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Preprint
Buchan M. et al, (2022)
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Journal article
Ellender TJ. et al, (2019), Nat Commun, 10
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Journal article
Buchan MJ. et al, (2021), J Neurophysiol, 125, 537 - 539
Recent publications
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GT4SD: Generative Toolkit for Scientific Discovery
Preprint
Manica M. et al, (2022)
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Preprint
Buchan M. et al, (2022)
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Journal article
Buchan MJ. et al, (2021), J Neurophysiol, 125, 537 - 539
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Journal article
Buchan MJ., (2020), J Physiol
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Journal article
Cheng Y. et al, (2020), Journal of Neurochemistry
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Journal article
Ellender TJ. et al, (2019), Nat Commun, 10
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Journal article
Buchan MJ. et al, (2019), J Physiol, 597, 4127 - 4129
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Journal article
Buchan MJ., (2018), Frontiers in Psychology, 9
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Journal article
Buchan MJ. and Rowland JM., (2018), J Neurosci, 38, 6609 - 6611
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Journal article
Ellender T. et al, (2018)