Colleges
Paolo Tammaro
Associate Professor in Pharmacology
- Fellow & Tutor in Medicine & Biomedical Sciences, The Queen's College
Key publications
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The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Journal article
Bushell SR. et al, (2019), Nat Commun, 10
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Defining the ionic mechanisms of optogenetic control of vascular tone by channelrhodopsin-2.
Journal article
Rorsman NJG. et al, (2018), Br J Pharmacol, 175, 2028 - 2045
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Contrasting effects of phosphatidylinositol 4,5-bisphosphate on cloned TMEM16A and TMEM16B channels.
Journal article
Ta CM. et al, (2017), Br J Pharmacol, 174, 2984 - 2999
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Mechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blocker.
Journal article
Ta CM. et al, (2016), Br J Pharmacol, 173, 511 - 528
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Coronary spasm and acute myocardial infarction due to a mutation (V734I) in the nucleotide binding domain 1 of ABCC9.
Journal article
Smith KJ. et al, (2013), Int J Cardiol, 168, 3506 - 3513
Recent publications
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The Ca2+-gated channel TMEM16A amplifies capillary pericyte contraction and reduces cerebral blood flow after ischemia
Journal article
Korte N. et al, (2022), Journal of Clinical Investigation
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TMEM16A channel is a key regulator of cerebral blood flow at the capillary level
Conference paper
Ilkan Z. et al, (2022), BIOPHYSICAL JOURNAL, 121, 176A - 176A
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Polymodal Control of TMEM16x Channels and Scramblases
Journal article
Agostinelli E. and Tammaro P., (2022), International Journal of Molecular Sciences, 23
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An outer-pore gate modulates the pharmacology of the TMEM16A channel.
Journal article
Dinsdale RL. et al, (2021), Proc Natl Acad Sci U S A, 118
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Ion channels as convergence points in the pathology of pulmonary arterial hypertension.
Journal article
Jouen-Tachoire TRH. et al, (2021), Biochem Soc Trans